Nutrition

Fish oil - how is it produced?

The process of extracting thefish oil cannot be the same as the process of extracting oil from, say, olives, because the starting food matrix is obviously different. The fish used to produce the oil are anchovies and sardines from open waters that undergo a rapid steam passage to coagulate the proteins and drain the liquids from the cells (water and oil) and are then mechanically cold pressed to collect theraw fish oil. However, raw fish oil goes through numerous processing steps before it is destined for human consumption.



The production process: multiple molecular distillation



Through Short Path Distillation (distillation at reduced pressure and thus reduced evaporation temperature) free fatty acids, heavy metals, colored compounds and other impurities are removed from the raw fish oil, making the oil much purer. During this process, concentration of the fish oils also takes place, leading to a total omega-3 content of 60 to 70 percent. The production of the pharmaceutical-grade concentrated oils requires several steps:


  1. Deacidification: this step removes free fatty acids, the cause of triglyceride breakdown through oxidation (rancidity)
  2. Ethylesterification (transformation to EE) and concentration: fatty acid ethyl esters are obtained by treating triglyceride oil with nonaqueous ethanol and a catalyst
  3. advanced molecular distillation: working under high vacuum lowers the boiling point of the ethyl esters, which makes it possible to separate long-chain fatty acids from short-chain fatty acids. This technique makes it possible to produce oils with different EPA/DHA concentrations and ratios.
  4. Fractionation to remove saturated fats
  5. Urea filtration: urea is added to the oil to form inclusion complexes with saturated and monounsaturated fatty acids. The complexes with urea are removed by filtration. The oil obtained after filtration has a higher concentration of EPA and DHA.
  6. decolorization: colored pigments and other oxidation compounds are removed from the oil. Decolorizing earths are added to the oil, which absorb these compounds and are then removed by filtration. If the raw fish oil contained high values of polycyclic aromatic hydrocarbons (PAHs), activated carbon will be added during this stage of the process to remove these compounds.
  7. Deodorization: The oil is deodorized by passing it through a steam stream working in a vacuum for a short period of time to remove the volatile components that are the main cause of the oil's taste and odor.
  8. Addition of vitamin E: Antioxidants in the form of natural tocopherols are added in accordance with the law.




Ethylation, for a high concentration of EPA and DHA


After the first deacidification step to concentrate the omega-3 fatty acids, an esterification reaction (ethylation) is made to take place. The chemical structure in which these omega-3 fatty acids are naturally found in fish oil is that of natural glycerides (TGs), and with ethylation they are transformed into EE ethyl esters with the formation of an oil rich in ethylEPA and ethylDHA that then undergoes the other listed steps. Many products on the market contain fish oils in EE form produced by the process just described. But Mequor 900 and Omegor Vitality products have unique characteristics.



Meaquor 1000 - medicinal alternative?


Specialty medicines such as L'Eskim, Seacor, or Esapent have an ethyl ester oil as does our product Meaquor 1000, which is designed as a dietary supplement with a high concentration of EPA and DHA to be used as an alternative to these specialty medicines when they cannot be prescribed under reimbursable conditions, offering savings in the cost of treatment.



Omegor Vitality - excellent quality


Our Omegor Vitality product, on the other hand, is made from a fish oil that undergoes an extra production step ( re-esterification using an enzymatic method) to restore the omega-3 fatty acids to the TG triglyceride form, the form that offers the most benefits and advantages:


  • improved absorption of actives
  • greater stability
  • improved digestibility of the product


This extra production step implies 50% to 80% higher costs compared to products in EE form. But it ensures an excellent quality product:


  • this production process yields oils in 90% triglyceride form that are most similar to natural fish oil, in which the triglyceride form accounts for 97-98% of the total fatty acids.


Attached are fact sheets for our product line. I remain available for further information. Sincerely, Rosaria Ramondino Pharmacist and Pharmaceutical Chemist.

Recommended products

Read more

D3 Drops 800UI

$10.00
D3 drops is a premium quality vitamin D3 dietary supplement - Which®-D* - free of gluten or other allergens that provides 800 IU of vitamin D3 per drop. It can be used in all cases of Increased need for or decreased dietary intake of vitamin D3.

 

Serving size: 1 drop per day
Number of servings: 70
Lot and expiration date: N/A

Read more

OMEGOR Classic

$15.00

Omegor Classic contains four important nutrients: omega-3 (EPA/DHA) and vitamins D, A and E. It is purified cod liver oil flavored with a pleasant taste of lemon and natural herbs. 

Quantità porzione: 5 ml
Numero di porzioni: 50
Lotto e scadenza: B0022984 – Aprile 2025


Read more

OMEGOR Kids - 60 capsules

$15.00

Omegor Kids capsule masticabili è un integratore alimentare di omega-3 DHA ed EPA con vitamine D3 ed E appositamente formulato per fornire ai bambini e adolescenti i componenti nutritivi necessari a favorire la crescita e lo sviluppo fisico, intellettivo e comportamentale. 

Quantitá porzione: 2
Numero di porzioni: 30
Lotto e scadenza: B0023514 - Ottobre 2025

Read more

RestoraFlor™ Liquid

$15.00

RestoraFlor Liquid is an innovative dietary supplement of probiotics and B vitamins in liquid form. RestoraFlor™ Liquid combines two of the probiotic strains with the strongest clinical evidence, Lactobacillus Rhamnosus GG and Saccharomyces Boulardii, with prebiotic fibers and vitamins B1, B2, B6 and B12. 

Quantitá porzione: 1
Numero di porzioni: 10
Lotto e scadenza: V40084 - Gennaio 2026