Ask the Pharmacist

Which supplement is best for preventing joint problems and maintaining overall well-being?

Good morning, I have some questions. I am a 40 year old man, Analysis ok, fish not so much.... 1) what dosage would you recommend for "general health" and "prevention" for joint problems? 2) what is the actual concentration of your products? In what ratio? One last business question: I followed the "zone" diet years ago,....why should I choose Vs. products instead of Enerzona products? See you soon. Thank you in advance. Riccardo 

Dear Richard, 

Our product line is mostly made up of dietary supplements containing EPA and DHA omega-3 fatty acids, but in each of them there are different concentrations and different ratios of EPA and DHA, depending on the indication and specificity of the product. For example, Omegor Vitality 1000 (packs of 30, 60, and 90 soft capsules) contains 1000 mg of fish oil per capsule and provides 535 mg of EPA, 268 mg of DHA, and 900 mg of total omega-3. The concentration per capsule of EPA + DHA is minimum 80%, while that of omega-3 fatty acids is 90%. 

The ratio of EPA to DHA is 2:1. This product because of the omega-3 content and the specific 2:1 ratio of EPA to DHA is used in the Zone Diet diet. To further confirm and guarantee the concentration of omega-3 EPA and DHA stated on the label and its purity and freshness, each batch of Omegor Vitality 1000 product is certified with 5 stars IFOS, the certification program specifically for fish oil supplements; the certificate of analysis of each batch is available for consultation (by searching the list for the name of our company UGA Nutraceuticals) on the website: https://certifications.nutrasource.ca/certified-products 

IFOS certification is also applied to Omegor Vitality 500, Meaquor and VitaDHA 1000 products. The reason why Omegor Vitality is the best choice among omega-3 fatty acid supplements is related not only to the exceptional purity, freshness and concentration values certified on all batches by IFOS, but also to the special molecular form of omega-3 fatty acids that results in a marked change in absorption and digestibility characteristics. 

Omegor Vitality is produced with a fish oil purified by multiple molecular distillation and omega-3 in the form of re-esterified triglycerides (rTG), the Enerzona product contains a fish oil with omega-3 in the form of ethyl esters (EE). The triglyceride (TG) form is the molecular form in which the fatty acids we ingest with food are found and therefore the one that our bodies are accustomed to digesting and assimilating and that gives no aftertaste. The ethyl ester (EE) form, on the other hand, is a molecular structure of fatty acids that does not exist in nature and is therefore poorly digestible because our bodies are not accustomed to processing it. Moreover, because of the volatile component represented by ethyl it causes an unpleasant fishy aftertaste. Several scientific studies,i have shown that omega-3 in the form of re-esterified triglycerides (rTG) are absorbed 70 percent more than omega-3 in the form of ethyl esters (EE).  

Omega-3s in the form of triglycerides such as those found in Omegor Vitality 1000 thus ensure better absorption and utilization of these fatty acids by the body and avoid the unpleasant fishy aftertaste. Regarding the dosage of omega-3 EPA and DHA useful for general well-being, following the European Commission's guidelines, 250 mg of EPA+DHA per day (thus 1 capsule per day ofOmegorVitality 1000) is sufficient for the maintenance of normal cardiac function while a dosage of 250 mg per day of DHA alone (2 capsules of Omegor Vitality 1000) is necessary for the maintenance of normal brain and visual function.In the case of joint problems, to take full advantage of the anti-inflammatory potential of omega-3 in a 2:1 ratio, the dosage I recommend is 2-3 capsules per day of Omegor Vitality 1000 to be taken near a main meal (breakfast, lunch, or dinner) for a period of at least 2 months.

Sincerely, 

Dr. Rosaria Ramondino Pharmacist and pharmaceutical chemist

Scientific Sources

  • Schuchardt, J. P., & Hahn, A. (2013). Bioavailability of long-chain omega-3 fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids., 89, 1-8. https://doi.org/10.1016/j.plefa.2013.03.010

  • Cholewski, M., Tomczykowa, M., & Tomczyk, M. (2018). A comprehensive review of chemistry, sources and bioavailability of omega-3 fatty acids. Nutrients, 10(11), 1662. https://doi.org/10.3390/nu10111662

  • Chevalier, L., Vachon, A., & Plourde, M. (2021). Pharmacokinetics of supplemental omega-3 fatty acids esterified in monoglycerides, ethyl esters, or triglycerides in adults in a randomized crossover trial. The Journal of Nutrition, 151, 1111-1118. https://doi.org/10.1093/jn/nxaa458

  • Dyerberg, J., Madsen, P., Møller, J. M., Aardestrup, I., & Schmidt, E. B. (2010). Bioavailability of marine n-3 fatty acid formulations. Prostaglandins, Leukotrienes and Essential Fatty Acids., 83, 137-141. https://doi.org/10.1016/j.plefa.2010.06.007

  • Krupa, K. N., Fritz, K., & Parmar, M. (2024). Omega-3 Fatty Acids. In StatPearls [Internet]. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK564314/